Effects of Maytenus senegalensis (L) and Cassia alata (L) Extracts on the Kidney Function Test Parameters of Albino Rats, Infected with Schistosomes Cercariae

Abstract

The aim of this investigation was to assess the kidney filtration as to ascertain the excretion of creatine and urea of albino rats which were subjected to the treatment with extracts of methanol and aqueous water extracts of Maytenus senegalensis and Cassia alata previously infected with schistosome cercariae. The normal values of creatine (160-1180µmol/l), and those of urea (10.7- 27.1µmol/l) were not affected. This is an indication that the function of the kidney was not alterred neither by the infection with schistosome nor by the treatment with plant extracts with methanol or water, however some treatments such as 9g/kg body weight produced patechial haemorhage.